The 2010 Mercedes-Benz E-Class has no open NHTSA recalls. Owners report 5 recurring issue clusters, led by “Transmission self-shifts to park while slowing.” Mercedes-Benz alternates two service events: Service A (oil, filter, inspection) at roughly 10,000 miles or 1 year, then Service B (Service A plus brake fluid, cabin filter, and deeper checks) at roughly 20,000 miles or 2 years — the ASSYST Plus counter in the cluster tells you which is due. Oil must carry the MB-Approval number your engine specifies (commonly 229.5, or 229.71 for newer 0W-20 engines); 'meets or exceeds' marketing language is not an approval. Electric EQB and EQS models keep the A/B rhythm for inspections, brake fluid, and cabin filters — just without oil.
No open recalls on file. NHTSA lists no unrepaired safety recalls for this year, make and model. A recall can be issued at any time, and a specific car can still have one open — check yours by VIN at nhtsa.gov/recalls.
What drivers and federal regulators have officially reported about the 2010 Mercedes-Benz E-Class.
POWER TRAIN, ELECTRICAL SYSTEM
15 NHTSA complaints · 2017-07 → 2025-11
“CAR SHIFTING FROM DRIVE OR REVERSE INTO PARK ON IT'S OWN”
“The contact owns a 2010 Mercedes-Benz E350. The contact stated that while driving at an undisclosed speed, the transmission shifted to PARK before the vehicle came to a full stop”
“THE VEHICLE SLAMS ITSELF INTO PARK WHEN MOVING UNDER 5MPH. THIS MOSTLY OCCURS WHEN TEMPERATURES ARE ABOVE ABOUT 75-80 DEGREES FAHRENHEIT”
FUEL/PROPULSION SYSTEM
22 NHTSA complaints · 2017-09 → 2025-04
“This is in regard to E350 2010. Gas smell after tank fill up (only when full). Fuel pump cover on the driver side under the back seat. The tank cover (plastic) breaks and leaks”
“THE VEHICLE EMIT A FUEL ODOR FROM THE REAR. THIS IS DUE TO FUEL LEAKS COMING FROM THE GAS TANK ASSEMBLY”
“FUEL ODOR AFTER REFUELING TO FULL TANK, GAS ODOR ONLY WHEN OUTSIDE OF CAR. NO GAS ODOR AFTER FUEL LEVEL HAS DROPPED ABOUT 1/8TH (7/8TH STILL IN TANK)”
SUSPENSION
16 NHTSA complaints · 2017-09 → 2021-02
“THE REAR SUSPENSION AIR BAGS, SOLENOID DISTRIBUTION VALVE AND AIRMATIC COMPRESSOR REQUIRE REPLACEMENT ACCORDING TO THE MERCEDES DEALERSHIP SERVICE DEPARTMENT. REAR SUSPENSION DROPS NEARLY TO THE GROUND WHILE VEHICLE IS STATIONARY AND VEHICLE IS UNSAFE TO OPERATE”
“THE AIR SUSPENSION INTERMITTENTLY DROPS THE CAR, RESULTING IN A WARNING LIGHT THAT SAYS CAR TOO LOW, PULL OVER. YOU HAVE TO STOP THE CAR WHEREVER IT HAPPENS IMMEDIATELY AS THE CAR IS SO LOW IT RUBS THE WHEELS ON THE WHEEL WELLS”
“MY CAR DROPS OVER NIGHT. SOME DAYS MY FRONT WOULD DROP TO THE FLOOR. SOME DAYS MY REAR AND SOME DAYS THE WHOLE CAR WILL BE ON THE FLOOR”
SUSPENSION, STRUCTURE, SERVICE BRAKES
32 NHTSA complaints · 2021-01 → 2026-04
“The contact owns a 2010 Mercedes-Benz E350. The contact stated while the contact's wife was driving at an undisclosed speed, the brake pedal was depressed, however, the vehicle failed to stop as intended”
“The contact owns a 2010 Mercedes-Benz E350. The contact stated that while driving at an undisclosed speed, the brake line fractured and the low brake fluid warning light illuminated; however, the contact stated he was able to stop the vehicle by depressing the brake pedal”
“Per the technician: "the rear subframe is rusted out and the lateral strut arm is starting to break away". Because of this issue, the car unknowingly presented a safety risk to occupants and other drivers”
AIR BAGS
78 NHTSA complaints · 2017-01 → 2019-10
“"TAKATA RECALL" I RECEIVED A RECALL LETTER FROM MERCEDES DATED MAY, 2016 REGARDING RECALL # 20160220003 FDRIVE-SIDE AIR BAG MODULE. NHTSA RECALL #16-V-081. IT HAS BEEN A YEAR AND I CONTACTED THEM REGARDING THIS ISSUE AND THEY STILL HAVE NO FIX AND NO ETA FOR A FIX”
“TAKATA RECALL (DRIVER'S SIDE AIRBAG)”
“TAKATA RECALL IN DEC 2017 I WAS NOTIFIED THAT MY AIRBAG INITIATORS REQUIRED REPLACEMENT AND PARTS WOULD BE AVAILABLE BY MARCH 31,2018. ACCORDING TO MERCEDES THEY HAVE NO IDEA AS OF TODAY (10/22/2018) WHEN THE PARTS WILL BE AVAILABLE”
Issues on other model years
Source: NHTSA Office of Defects Investigation (ODI). Complaint data refreshed Sep 20, 2026. Investigation data refreshed Sep 20, 2026.
We display NHTSA's record with attribution; we don't editorialize on what these complaints mean for any specific vehicle.
Critical for safety and preventing major damage
Every 10,000 miles or 12 months: oil and filter with MB-Approved oil, fluid top-offs, tire check, and inspection. AMG models driven hard: many owners service at 5,000-7,500 miles.
Estimated cost — typical U.S. ranges
Dealer
~$120–$160
Shop
~$85–$115
DIY
~$25–$55
Full synthetic costs more than conventional. 5-quart 0W-20 + filter is the typical bill.
Every 20,000 miles or 2 years, alternating with Service A: everything in A plus brake-fluid replacement, cabin filter, and a deeper multi-point inspection of brakes, suspension, and driveline.
Estimated cost — typical U.S. ranges
Dealer
~$85
Shop
~$60
DIY
Free
Most shops do this free with any paid service. A flashlight and 10 minutes covers the basics yourself.
Rotate at every Service A where the tire sizes allow. Many AMG and 4MATIC+ models run staggered widths that can't rotate front-to-rear — check your spec before paying for a rotation.
Estimated cost — typical U.S. ranges
Dealer
~$85
Shop
~$60
DIY
Free
Often free at the shop where you bought the tires — worth asking before paying.
Checked at every A/B service via electronic pad-wear sensors. Replace sensors with pads. Heavy EQS models wear pads slowly (regen braking) but rotors can corrode from disuse — an inspection catches that.
Estimated cost — typical U.S. ranges
Dealer
~$85
Shop
~$60
DIY
Free
Most shops do this free as a courtesy with any service. Don't pay separately if you can avoid it.
Replaced every 2 years as part of Service B — Mercedes schedules it on time, not miles, because DOT 4 fluid absorbs moisture regardless of driving.
Estimated cost — typical U.S. ranges
Dealer
~$180–$200
Shop
~$125–$140
DIY
~$10–$25
DOT 3 or 4 — match the cap. Vacuum bleeders make this a one-person DIY.
Keeps your vehicle running smoothly and efficiently
Mercedes specifies fluid and filter service around 70,000 miles on most 7G- and 9G-Tronic gearboxes — check your year's sheet. Use only the MB-spec fluid for your transmission code; independent specialists often service at 60,000 on hard-driven cars.
Estimated cost — typical U.S. ranges
Dealer
~$330–$500
Shop
~$235–$355
DIY
~$60–$180
Some sealed transmissions have no dipstick — fill is precise and best left to a shop. Many drivers can still DIY drain-and-fill.
Most modern MB gas engines: plugs around 60,000 miles — AMG engines often sooner. Check your engine's sheet; twin-turbo V8 plug jobs are labor-heavy, so pair with other scheduled work.
Estimated cost — typical U.S. ranges
Dealer
~$285–$390
Shop
~$200–$275
DIY
~$25–$100
Iridium plugs cost more but last 100k+ miles. V6/V8 access varies wildly — some are tough.
Replace around every 40,000 miles (twin-filter setups on V6/V8 engines double the parts bill). Inspected at every Service B.
Estimated cost — typical U.S. ranges
Dealer
~$60–$95
Shop
~$45–$70
DIY
~$15–$40
5-minute job on most cars; the airbox lid usually has clips, no tools needed.
Extends the life of your vehicle and improves comfort
Replaced with every Service B. Models with the ENERGIZING air package use a higher-grade filter — priced accordingly.
Estimated cost — typical U.S. ranges
Dealer
~$60–$95
Shop
~$45–$70
DIY
~$15–$40
Usually behind the glovebox. Shops charge labor for a 10-minute job — easy DIY win.
MB-spec coolant is long-life (typically ~10 years / 150,000 miles on the sheet). Refresh only with MB 325/326-spec coolant — the wrong chemistry attacks aluminum and head gaskets.
Estimated cost — typical U.S. ranges
Dealer
~$285–$330
Shop
~$200–$235
DIY
~$25–$60
Use the manufacturer-specified coolant — wrong color/chemistry can damage the cooling system.
Test annually after year 3. Most modern Mercedes carry a second auxiliary battery; a weak one triggers cascading warning messages long before a no-start. EQ models also depend on the 12V system to boot.
Estimated cost — typical U.S. ranges
Dealer
~$225–$390
Shop
~$160–$280
DIY
~$130–$250
Most auto-parts stores test and install batteries free with purchase. Skip the dealer markup.
Occupant deaths in fatal crashes (FARS)
42 crashes 1990–2024
How the 42 occupant deaths break down
32
driver deaths
10
passenger deaths
42
occupant deaths
Crash years covered: 1990–2024 This model year first appears in 2010 crashes. Older models have had more years on the road to appear in these crashes, so a higher count here does not by itself mean a vehicle is less safe.
FARS counts every occupant death in a fatal crash, whatever the cause — it does not mean the vehicle was at fault or defective. Counts are not adjusted for how many of each vehicle are on the road. How to read this number
FARS 2024 data is an annual report file. NHTSA revises these records when the final file is published, so this count can change.
Every vehicle has exactly one driver seat, so driver deaths line up fairly when you compare one model to another. Occupant deaths include passengers, so a three row SUV can show a higher number than a two seat car simply because it carries more people.
Both figures are plain counts, not rates. A rate would need to know how many of each vehicle are on the road, and that registration data is not public, so we do not publish rates or scores of any kind.
IIHS publishes driver death rates using this same driver only idea, paired with a registered vehicle years denominator we do not have. Their rates and these counts answer different questions, so do not read either number here as a safety rating.
Owner-reported problem signals
Separate from the federal fatality data above: complaints owners filed with NHTSA about this year and model. These are reports of problems, unverified, and are counted here only as signals.
9
complaints mentioning a crash
0
complaints mentioning a fire
Typical U.S. ranges. Actual quotes vary by shop, parts choice, and vehicle condition.
How we estimate: Dealer = OEM parts × 1.4 + labor × $165/hr. Shop = parts + labor × $115/hr. DIY = parts only.
This maintenance schedule for the 2010 Mercedes-Benz E-Class reflects Mercedes-Benz's published service intervals and the ASSYST Plus (Service A / Service B) system. Your actual service needs may vary based on driving conditions, climate, and vehicle usage. Always consult your owner's manual for model-specific recommendations.